2025

Bourgonje AR, Mian P. Advancing Proactive Therapeutic Drug Monitoring with Model-Informed Precision Dosing in Pediatric Crohn’s Disease. Clin Gastroenterol Hepatol. 2025:S1542-3565(25)00666-4. doi: 10.1016/j.cgh.2025.06.046.

Bourgonje AR, Ibing S, Rajauria P, Peraza J; Mild CD Investigation Consortium; Colombel JF, Ungaro RC. Mild Crohn’s Disease is Associated with Altered Sphingolipid Metabolism and Reduced Neutrophilic Inflammation. Gastroenterology. 2025:S0016-5085(25)05731-2. doi: 10.1053/j.gastro.2025.06.026.

Bourgonje AR, Andreu-Sánchez S, Gacesa R, Innocenti G, Kalka IN, Klompus S, Leviatan S, Schlesinger Y, Krongauz D, Weinberger A, van der Vegt B, Fu J, Segal E, Zhernakova A, Vogl T, Weersma RK. Crohn’s disease and ulcerative colitis exhibit prediagnostic antibody signatures with shared and divergent changes towards disease onset. Gut. 2025:gutjnl-2024-334362. doi: 10.1136/gutjnl-2024-334362.

Te Lintelo AM, van Wier LF, van der Doef HPJ, Kosterink JGW, Scheenstra R, van Leer CC, Bourgonje AR, Touw DJ, Mian P. Tacrolimus Trough Concentrations are Not Impacted by Epstein-Barr Virus Serology and Viral Load in Pediatric Liver Transplant Recipients. Eur J Drug Metab Pharmacokinet. 2025. doi: 10.1007/s13318-025-00954-3. 

Bourgonje AR. Dualistic Implications of Angiotensin-Converting Enzyme 2 (ACE2) Expression in Inflammatory Bowel Disease. Inflamm Bowel Dis. 2025:izaf131. doi: 10.1093/ibd/izaf131. 

Vlaming-van Eijk LE, Tang G, Bourgonje AR, den Dunnen WFA, Hillebrands JL, van Goor H. Post-COVID-19 condition: clinical phenotypes, pathophysiological mechanisms, pathology, and management strategies. J Pathol. 2025;266(4-5):369-389. doi: 10.1002/path.6443.

Trzpis M, Zernova M, Vermeulen KM, Bulthuis MLC, Reinders-Luinge M, van Goor H, van Munster BC, Bourgonje AR. Systemic oxidative stress associates with delirium in a geriatric population with hip fracture. Exp Gerontol. 2025;207:112801. doi: 10.1016/j.exger.2025.112801.

Bourgonje AR, Ibing S, Livanos AE, Ganjian DY, Argmann C, Sands BE, Dubinsky MC, Helmus DS, Jacobsen HA, Larsen L, Jess T, Suarez-Fariñas M, Renard BY, Colombel JF, Ungaro RC. Distinct perturbances in metabolic pathways associate with disease progression in inflammatory bowel disease. J Crohns Colitis. 2025;19(6):jjaf082. doi: 10.1093/ecco-jcc/jjaf082.

Kirchgesner J, Verstockt B, Adamina M, Allin KH, Allocca M, Bourgonje AR, Burisch J, Doherty G, Dulai PS, El-Hussuna A, Misra R, Noor N, Pittet V, Powell N, Rodríguez-Lago I, Restellini S. ECCO Topical Review on Predictive Models on Inflammatory Bowel Disease Disease Course and Treatment Response. J Crohns Colitis. 2025;19(6):jjaf073. doi: 10.1093/ecco-jcc/jjaf073.

Holstein HJ, Bouwknegt DG, Visschedijk MC, Bulthuis MLC, Reinders-Luinge M, Schoots MH, van Goor H, Gordijn SJ, Dijkstra G, Bourgonje AR. Exploring biomarkers of systemic oxidative stress and placental insufficiency in pregnant women with inflammatory bowel diseases. Free Radic Biol Med 2025;232:319-329. doi: 10.1016/j.freeradbiomed.2025.03.017. 

Su F, Su M, Wei W, Wu J, Chen L, Sun X, Liu M, Sun S, Mao R, Bourgonje AR, Hu S. Integrating multi-omics data to reveal the host-microbiota interactome in inflammatory bowel disease. Gut Microbes. 2025;17(1):2476570. doi: 10.1080/19490976.2025.2476570.

Bourgonje AR, Kayal M. Understanding the Impact of Prior Anti-TNF Exposure on Colectomy Risk in Acute Severe Ulcerative Colitis. Dig Dis Sci 2025; in press. doi: 10.1007/s10620-025-08930-2.

Bourgonje AR, Knobbe TJ, Kremer D, Bulthuis MLC, Bemelman FJ, Berger SP, Navis GJ, Bakker SJL, Corpeleijn E, van Goor H; ACTx collaborators. Effect of lifestyle intervention on systemic oxidative stress in kidney transplant recipients: A post-hoc analysis of the Active Care after Transplantation (ACT) randomized controlled trial. Free Radic Biol Med 2025;232:412-420. doi: 10.1016/j.freeradbiomed.2025.03.002.

Wang KY, Heikal OS, van Rheenen PF, Touw DJ, Bourgonje AR, Mian P. Clinical and Biochemical Factors Associated with Infliximab Pharmacokinetics in Paediatric Patients with Inflammatory Bowel Disease. J Clin Med 2025;14(3):845. doi: 10.3390/jcm14030845.

Bourgonje AR, Posner H, Carbonnel F, Colombel JF, Kayal M. Prior Anti-TNF Exposure Is Associated with an Increased Risk of Short- and Long-Term Colectomy in Acute Severe Ulcerative Colitis. Dig Dis Sci 2025;70(2):738-745. doi: 10.1007/s10620-024-08809-8.